Amlodipine, sold under the brand name Norvasc among others, is a medication used to treat high blood pressure and coronary artery disease. While calcium channel blockers are not typically recommended in heart failure, amlodipine may be used if other medications are not sufficient for high blood pressure or heart related chest pain. Amlodipine is taken by mouth and has an effect for at least a day.
Common side effects include: swelling, feeling tired, abdominal pain, and nausea. Serious side effects may include low blood pressure or a heart attack. It is unclear if use is safe during pregnancy or breastfeeding. Doses should be decreased in people with liver problems and those who are old. Amlodipine is a long acting calcium channel blocker of the dihydropyridine type. It works partly by increasing the size of arteries.
Medical uses
Amlodipine is used in the management of hypertension[7] and coronary artery disease (chronic stable angina, vasospastic angina, and angiographically documented CAD without heart failure or ejection fraction < 40%.) It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease. Amlodipine can be administered to adults and children 6–17 years of age.
Appearance White or almost white powder
Identification Meets the requirements
Specific Rotation -0.10 ~ +0.10°
Water ≤0.5%
Heavy Metals ≤0.002%
Redidue in Ignition ≤0.2%
Related Substances Meets the requirements
Benzene Sulfonic Acid 27.3 ~ 28.7%
Ethanol ≤300ppm
Toluene ≤60ppm
Benzene ≤2ppm
Acetic Acid ≤600ppm
Methylamine ≤20ppm
Ethyl Benzene Sulfonate ≤5ppm
Particle Size Meets the requirements
Assay 98.0 ~102.0%
Standard USP33

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body