Gefitinib.jpg
Gefitinib (ZD1839) (INN, /ɡɛˈfɪtᵻnɪb/, trade name Iressa) is a drug used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR. It is marketed by AstraZeneca and Teva.
Product Detailed
Name: Gefitinib
CAS No.: 184475-35-2
Formula: C22H24ClFN4O3
Molecular Weight: 446.90 .
Synonyms:N-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;ZD1839;4-(3-Chloro-4-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline;Irressat;Gefitinib (JAN/USAN);4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-;ZD 1839;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;
Density: 1.322 g/cm3
Melting Point: 119-120 °C
Boiling Point: 586.8 °C at 760 mmHg
Flash Point: 308.7 °C
Appearance: light-yellow crystalline powder
Product name
Gefitinib
CAS NO.
184475-35-2
Description
White or almost white powder
Melting point
188°C~193°C
Loss on drying
£1.0%
Residue on ignition
£0.1%
Assay
≥99.0%
SPECIFICATIONS:
 ITEMS
SPECIFICATIONS
RESULTS
Description
Slight white to white crystalline powder
White crystalline powder
Identification(IR)
Conforms to the reference
Cnforms to th reference
Melting piont
194.0~198.0℃
195.5~197.0℃
Water (KF)
0.30%
0.21%
Individual purity
0.50%
0.15%
Assay (HPLC)
99%
99.28%
Conclusion
Complies with Enterprise standard
Packing and storage:
Storage: Store in cool & dry place, Keep away from strong light and heat.
Shelf life: 24 Months when properly stored.
Packing: Paper-drums for outer and two plastic-bags inside
N.W.: 25 kgs
G.W.:28 kgs
Delivery: within two weeks after receiving your prepayment.

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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