Tedizolid phosphate.png
Tedizolid (formerly torezolid, trade name Sivextro), is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid. It was developed by Cubist Pharmaceuticals, following acquisition of Trius Therapeutics (originator: Dong-A Pharmaceuticals), and is marketed for the treatment of acute bacterial skin and skin structure infections (also known as complicated skin and skin-structure infections (cSSSIs)).
Tedizolid has been approved by the U.S Food and Drug Administration on June 20, 2014, for the treatment of acute bacterial Skin and skin structure infections (ABSSSI) caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains, MRSA, and methicillin-susceptible strains), various Streptococcus species (S. pyogenes, S. agalactiae, and S. anginosus group including S. anginosus, S. intermedius, and S. constellatus), and Enterococcus faecalis. Tedizolid is a second-generation oxazolidinone derivative that is 4-to-16-fold more potent against staphylococci and enterococci compared to linezolid. The recommended dosage for treatment is 200 mg once daily for a total duration of six days, either orally (with or without food) or through an intravenous injection (if patient is older than 18 years old).
Mechanism of action
Tedizolid phosphate (TR-701) is a prodrug activated by plasma or intestinal phosphatases to tedizolid (TR-700) following administration of the drug either orally or intravenously. Once activated, tedizolid exerts its bacteriostatic microbial activity through inhibition of protein synthesis by binding to the 50S ribosomal subunit of the bacteria.

Product Description:

Product Name Tedizolid phosphate
Synonyms TR 701FA; (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone
CAS Number 856867-55-5
Molecular Structure
Molecular Formula C17H16FN6O6P
Molecular Weight 450.32
Form White Powder


Tests Analysis Standard Results
Description White or slightly yellowish powder off-white powder
IR Identification The infrared absorption spectrum is concordant with the reference spectrum of standard Conforms
Content 98.0% to 101.0% 99.0%
Water ≤1.0% 0.05%
General Conclusion Be Conform With Enterprise Standard

Packing & Delivery:

(1) 10g/100g/500g/1kg, packaged by Aluminum foil bag.
(2) Customized package.
Delivery: Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea. Please allow 5-8 days by Air, 15-30 days by Sea.
For small order, please expect 3-7 days by UPS DHL EMS.
Depending on your location, please allow 1-5 business days for your order to arrive.

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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body