Vonoprazan fumarate.jpg
Vonoprazan fumarate is a first-in-class potassium-competitive acid blocker. It was approved in the Japanese market in February 2015.
Vonoprazan can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori.
Product Description:
Product name
Vonoprazan fumarate
CAS NO.
881681-00-1
Synonyms
Vonoprazan fumarate
Category
Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Standard
purity:>99%
Appearance
Vonoprazan fumarate powder
Shelf life
2 years
Usage
Vonoprazan fumarate shows strong and sustainable acid secretion inhibitory effects as well as demonstrate efficacy in early termination by inhibiting the binding of potassium ion (K+) to H+, K+-ATPase (proton pump) in the final step of gastric acid secretion in gastric parietal cells.
Storage
Vonoprazan fumarate should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Specification:
TEST
SPECIFICATION
RESULT
Appearance
White to off-white crystals
White crystals
Identification
1-HNMR: Consistent with the standard
Conforms
HPLC: The HPLC spectrum of the sample must be concordant with the standard substance.
Conforms
Ignition residue
NMT 0.1%
Conforms
Heavy Metals
NMT 20ppm
N.D.
Loss on drying
NMT 1.0%
0.16%
Related Substance
U2: NMT 0.2%
0.03%
U3: NMT 0.3%
0.04%
U4: NMT 0.2%
N.D.
U6: NMT 0.5%
N.D.
U8: NMT 0.4%
N.D.
U9: NMT 0.25%
0.04%
Any other impurity: NMT 0.15%
0.05%
Total impurities: NMT 0.19%
0.23%
Residual Solvents
Methanol: NMT 0.3%
N.D.
Ethanol: NMT 0.5%
N.D.
Ethyl acetate: NMT 0.5%
N.D.
Assay(By HPLC)
98.0%~102%
99.78%
Storage
Store in a tightly closed container in a cool and dry place, below 20℃.
Conclusion
Confirm to enterprise standard

Packaging & Shipping:

Packaging:
1g/bag, 100g/bag, 1kg/bag, 25kg/drum
or other quantity just as you requests.
Shipping methods:
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Notice: This product is only suitable for laboratory use, or the use of animals. It can not be used directly on the human body

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