5-APB (abbreviation of “5-(2-aminopropyl)benzofuran”; see infobox for the correct IUPAC name) is an empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes. 5-APB and other compounds are sometimes informally called “Benzofury”.
5-APB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass and doses should be adjusted accordingly.
5-APB is a serotonin–norepinephrine–dopamine reuptake inhibitor with Ki(NET)=180 nmol/L, Ki(DAT)=265 nmol/L and Ki(SERT)=811 nmol/L. It is also a serotonin–norepinephrine–dopamine releasing agent. 5-APB is a potent agonist for the 5-HT2A and 5-HT2B receptors (Ki of 14 nmol/L at 5-HT2B with an efficacy of 0.924). This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA. 5-APB is also an agonist of the 5-HT2C receptor.
Product Name: 5-EAPB
Molecular weight: 239.78
Compound purity: > 99.7%
Application: For chemical research
Appearance: White powder
Related substance: Total Impurities(%) ≤ 0.3%
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Notice: This product is only suitable for laboratory use, or the use of animals. It c